Alzheimer disease in low polygenic risk score (<50th percentile)
MIR3171HG · rs895919483
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 2,232 European ancestry cases, 3,092 European ancestry controls.
The effect
Each copy of the C allele carried 76.89 times the odds of Alzheimer disease in low polygenic risk score (<50th percentile) (95% confidence interval 16.4381877523704-359.68956856127); p = 3 × 10−8.
Where it sits Chromosome 14, band 14q12 — in a non-coding transcript of MIR3171HG.
What each result means
C/CTwo copies of the version the research linked to Alzheimer disease in low polygenic risk score (<50th percentile). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Alzheimer disease in low polygenic risk score (<50th percentile). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Alzheimer disease in low polygenic risk score (<50th percentile). This is the starting point the study compared everyone against.
Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026 · PMID 42557982 · open access
Questions about rs895919483
What is rs895919483?
rs895919483 is a single position in the genome, in or near the MIR3171HG gene. Published research associates it with alzheimer disease in low polygenic risk score (<50th percentile). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs895919483 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs895919483 come from?
GWAS Catalog, Alzheimer's & dementia : the journal of the Alzheimer's Association 2026, PMID:42557982. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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