Sensitive

IgG4-related Mikuliczs disease

near CAPZA3 · rs894063168

Where this position leads

Condition: IgG4-Related Disease

rs894063168 Condition: IgG4-Related Disease IgG4-Related Disease Condition rs894063168 rs894063168 near CAPZA3

What the study found

Who was studied 363 Hondo Japanese ancestry cases, 2,659 Hondo Japanese ancestry controls.

The effect Each copy of the T allele carried 12.57 times the odds of IgG4-related Mikuliczs disease (95% confidence interval 5.11-30.93); p = 4 × 10−8.

How common The T allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 12, band 12p12.3 — between genes, 78.5 kb from CAPZA3.

What each result means

C/C No copy of the version the research linked to IgG4-related Mikuliczs disease. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to IgG4-related Mikuliczs disease. That is a smaller link than two copies.
T/T Two copies of the version the research linked to IgG4-related Mikuliczs disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs894063168

What is rs894063168?

rs894063168 is a single position in the genome, in or near the near CAPZA3 gene. Published research associates it with igg4-related mikuliczs disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs894063168 linked to?

On MyGeneLog this position is linked to IgG4-Related Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs894063168 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs894063168 come from?

GWAS Catalog, The Lancet. Rheumatology 2026, PMID:41197642. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

IgG4-related Mikuliczs disease (rs894063168). MyGeneLog™. https://www.mygenelog.com/variants/rs894063168

← See all variants