Who was studied 360,116 European ancestry individuals, 165,419 East Asian ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0106 lower (95% confidence interval 0.0073-0.0139); p = 2 × 10−10.
Where it sits Chromosome 3, band 3q26.1 — between genes, 149.7 kb from LINC01324.
What each result means
G/GPublished research associates this genotype with typical/baseline likelihood of Weight — no copies of the reported risk allele.
G/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Weight.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Weight compared to the general population.
rs892761 is a single position in the genome, in or near the near LINC01324 gene. Published research associates it with weight. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs892761 linked to?
On MyGeneLog this position is linked to Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.
Does having rs892761 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs892761 come from?
GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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