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Fasting glucose

ARHGAP1 · rs8914

What the study found

Who was studied 200,622 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0195 higher; p = 4 × 10−13.

How common The A allele had a frequency of about 11% in the people studied.

Where it sits Chromosome 11, band 11p11.2 — in the 3′ untranslated region of ARHGAP1.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Fasting glucose compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Fasting glucose.
G/G Published research associates this genotype with typical/baseline likelihood of Fasting glucose — no copies of the reported risk allele.
Source

Questions about rs8914

What is rs8914?

rs8914 is a single position in the genome, in or near the ARHGAP1 gene. Published research associates it with fasting glucose. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs8914 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs8914 come from?

GWAS Catalog, Nature genetics 2021, PMID:34059833. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Fasting glucose (rs8914). MyGeneLog™. https://www.mygenelog.com/variants/rs8914

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