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Male-pattern baldness

near APCDD1 · rs88943

Where this position leads

Condition: Androgenetic Alopecia (Male Pattern Baldness)

rs88943 Condition: Androgenetic Alopecia (Male Pattern Baldness) Androgenetic Alopecia (Male Pattern… Condition rs88943 rs88943 near APCDD1

What the study found

Who was studied 205,327 European ancestry males.

The effect Each copy of the T allele shifted the measure 0.0366 lower (95% confidence interval 0.03-0.043); p = 2 × 10−30.

How common The T allele had a frequency of about 39% in the people studied.

Where it sits Chromosome 18, band 18p11.22 — between genes, 51.2 kb from LINC01254.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Male-pattern baldness — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Male-pattern baldness.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Male-pattern baldness compared to the general population.
Source

Questions about rs88943

What is rs88943?

rs88943 is a single position in the genome, in or near the near APCDD1 gene. Published research associates it with male-pattern baldness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs88943 linked to?

On MyGeneLog this position is linked to Androgenetic Alopecia (Male Pattern Baldness). The research behind each link, and its sources, are set out on that condition page.

Does having rs88943 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs88943 come from?

GWAS Catalog, Nat Commun 2018, PMID:30573740. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Male-pattern baldness (rs88943). MyGeneLog™. https://www.mygenelog.com/variants/rs88943

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