0 00Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others0Total0Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
ClinVar classifies it as disease-causing (or likely), reviewed at 0 of 4 stars.
How this is scored
4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.
What ClinVar records
ClassificationLikely pathogenic for Autosomal recessive polycystic kidney disease; no assertion criteria provided (0 of 4 stars, 1 submitter).
ClinVar record 266005NM_138694.4(PKHD1):c.1472A>C (p.His491Pro)
Change history
MyGeneLog™ keeps a copy of every weekly release from 2026-10-19 and compares them. This position's classification has not changed since.
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
G/GTwo copies of the version ClinVar lists as likely disease-causing for Autosomal recessive polycystic kidney disease. A result like this should be confirmed by a medical genetic test and talked through with a doctor; consumer DNA files can misread rare variants. This call was sent to ClinVar without the lab's criteria, the least certain kind of record, so it may change. (ClinVar VCV000266005, no assertion criteria provided)
G/TOne copy of the version ClinVar lists as likely disease-causing for Autosomal recessive polycystic kidney disease. Some conditions need only one copy; for others, one copy makes a person a carrier who is usually healthy but can pass it on. A genetic counsellor can say which applies. This call was sent to ClinVar without the lab's criteria, the least certain kind of record, so it may change. (ClinVar VCV000266005, no assertion criteria provided)
T/TNo copy of the version ClinVar lists as likely disease-causing for Autosomal recessive polycystic kidney disease. This is the usual result. This call was sent to ClinVar without the lab's criteria, the least certain kind of record, so it may change. (ClinVar VCV000266005, no assertion criteria provided)
Source: ClinVar VCV000266005, no assertion criteria provided
Questions about rs886039888
What is rs886039888?
rs886039888 is a single position in the genome, in or near the PKHD1 gene. Published research associates it with autosomal recessive polycystic kidney disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs886039888 linked to?
On MyGeneLog this position is linked to Autosomal Recessive Polycystic Kidney Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs886039888 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs886039888 come from?
ClinVar VCV000266005, no assertion criteria provided. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 00Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others0Total0Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.