Gene Knowledge Graph
UTC
Sensitive

Multiple sclerosis

NR1D1 · rs883871

Where this position leads

Condition: Multiple Sclerosis

rs883871 Condition: Multiple Sclerosis Multiple Sclerosis Condition rs883871 rs883871 NR1D1

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Multiple sclerosis compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Multiple sclerosis.
G/G Published research associates this genotype with typical/baseline likelihood of Multiple sclerosis — no copies of the reported risk allele.
Source
Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility
International Multiple Sclerosis Genetics Consortium
Science (New York, N.Y.) · 2019 · PMID 31604244

Questions about rs883871

What is rs883871?

rs883871 is a single position in the genome, in or near the NR1D1 gene. Published research associates it with multiple sclerosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs883871 linked to?

On MyGeneLog this position is linked to Multiple Sclerosis. The research behind each link, and its sources, are set out on that condition page.

Does having rs883871 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs883871 come from?

GWAS Catalog, Science 2019, PMID:31604244. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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