Links from this page to related variants, conditions, drugs and topics are not included for automated readers. Those connections are the Gene Knowledge Graph and are licensed as data: https://www.mygenelog.com/license

Standard

Height

near PIEZO1P2 · rs878049

Strength of the evidence

2 / 4

Its strongest genetic-study result is p = 10−48, with 1 associations in the GWAS Catalog.

How this is scored

4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.

What the study found

Who was studied 472,730 East Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0578 lower (95% confidence interval 0.05-0.066); p = 2 × 10−48.

How common The A allele had a frequency of about 10% in the people studied.

Where it sits Chromosome 20, band 20q13.32 — between genes, 6.8 kb from PIEZO1P2.

How common each version is

AC
Korean KRGDB
A 11.2% · C 88.8%
Korean Korea4K
A 12.1% · C 87.9%
Korean Korea1K
A 12.2% · C 87.8%
Japanese ToMMo
A 8.6% · C 91.4%
Vietnamese
A 13.4% · C 86.6%
World gnomAD
A 13.3% · C 86.7%
World 1000 Genomes
A 9.8% · C 90.2%
World TOPMed
A 12.3% · C 87.7%

The share of all copies of this position that are each version. Source: the population studies published in dbSNP (US NCBI); each row names its study.

What each result means

A/A Two copies of the version the research linked to Height. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Height. That is a smaller link than two copies.
C/C No copy of the version the research linked to Height. This is the starting point the study compared everyone against.
Source

Quoting this page

Licensed CC BY-NC 4.0: free to read, share and adapt for non-commercial use, naming MyGeneLog™ and linking the exact page. Commercial use, including training or serving a commercial AI system, needs a licence — https://www.mygenelog.com/license

Height (rs878049). MyGeneLog™. https://www.mygenelog.com/variants/rs878049

← See all variants