Standard
Multiple myeloma
CBX7 · rs877529
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Multiple myeloma compared to the general population.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Multiple myeloma.
G/G
Published research associates this genotype with typical/baseline likelihood of Multiple myeloma — no copies of the reported risk allele.
Source
Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk
Chubb D,
Weinhold N,
Broderick P,
Chen B,
Johnson DC,
Försti A,
Vijayakrishnan J,
Migliorini G,
Dobbins SE,
Holroyd A,
Hose D,
Walker BA
and 23 more — show all
Davies FE,
Gregory WA,
Jackson GH,
Irving JA,
Pratt G,
Fegan C,
Fenton JA,
Neben K,
Hoffmann P,
Nöthen MM,
Mühleisen TW,
Eisele L,
Ross FM,
Straka C,
Einsele H,
Langer C,
Dörner E,
Allan JM,
Jauch A,
Morgan GJ,
Hemminki K,
Houlston RS,
Goldschmidt H
Nature genetics · 2013 · PMID 23955597 · open access
Questions about rs877529
What is rs877529?
rs877529 is a single position in the genome, in or near the CBX7 gene. Published research associates it with multiple myeloma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs877529 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs877529 come from?
GWAS Catalog, Nat Genet 2013, PMID:23955597. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants