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Body mass index

MRPL3 · rs876424

Where this position leads

Condition: Obesity and Body Weight

rs876424 Condition: Obesity and Body Weight Obesity and Body Weight Condition rs876424 rs876424 MRPL3

What the study found

Who was studied up to 309,889 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0189 lower (95% confidence interval -); p = 1 × 10−9.

How common The T allele had a frequency of about 65% in the people studied.

Where it sits Chromosome 3, band 3q22.1 — in an intron of CPNE4.

What each result means

G/G No copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Body mass index. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs876424

What is rs876424?

rs876424 is a single position in the genome, in or near the MRPL3 gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs876424 linked to?

On MyGeneLog this position is linked to Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.

Does having rs876424 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs876424 come from?

GWAS Catalog, PLoS Genet 2015, PMID:26426971. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Body mass index (rs876424). MyGeneLog™. https://www.mygenelog.com/variants/rs876424

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