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Who was studied 178 Japanese ancestry cases, 906 Japanese ancestry controls; replicated in 621 Japanese ancestry cases, 2,271 Japanese ancestry controls.
The effect
Each copy of the C allele carried 1.77 times the odds of Keloid (95% confidence interval 1.58-1.99); p = 6 × 10−23.
How common The C allele had a frequency of about 28% in the people studied.
Where it sits Chromosome 1, band 1q41 — between genes, 33.6 kb from LINC01705.
What each result means
C/CTwo copies of the version the research linked to Keloid. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Keloid. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Keloid. This is the starting point the study compared everyone against.
rs873549 is a single position in the genome, in or near the near LINC01705 gene. Published research associates it with keloid. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs873549 linked to?
On MyGeneLog this position is linked to Keloid. The research behind each link, and its sources, are set out on that condition page.
Does having rs873549 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs873549 come from?
GWAS Catalog, Nature genetics 2010, PMID:20711176. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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