CACNA1C · rs868105448
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 587 African American or Afro-Caribbean cases, 119,867 African American or Afro-Caribbean controls, 3,326 European ancestry cases, 441,653 European ancestry controls, 259 Hispanic or Latin American cases, 59,089 Hispanic or Latin American controls.
The effect Each copy of the C allele shifted the measure 2.79 lower (95% confidence interval 2.76-2.82); p = 3 × 10−15.
How common The C allele had a frequency of about 100% in the people studied.
Where it sits Chromosome 12, band 12p13.33 — in an intron of CACNA1C.
rs868105448 is a single position in the genome, in or near the CACNA1C gene. Published research associates it with pneumonitis due to inhalation of food or vomitus (phecode 501). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Pneumonitis due to inhalation of food or vomitus (PheCode 501) (rs868105448). MyGeneLog™. https://www.mygenelog.com/variants/rs868105448