Alzheimer's disease or family history of Alzheimer's disease
PICALM · rs867611
2 331422123Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot4Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others23Total33Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 24,087 European ancestry late-onset Alzheimer's disease cases, 47,793 European ancestry individuals with family history of Alzheimer's disease, 383,378 European ancestry controls.
The effect
Each copy of the G allele shifted the measure 8.75 z-unit lower; p = 2 × 10−18.
How common The G allele had a frequency of about 31% in the people studied.
Where it sits Chromosome 11, band 11q14.2 — in an intron of PICALM.
What each result means
A/ANo copy of the version the research linked to Alzheimer's disease or family history of Alzheimer's disease. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Alzheimer's disease or family history of Alzheimer's disease. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Alzheimer's disease or family history of Alzheimer's disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs867611 is a single position in the genome, in or near the PICALM gene. Published research associates it with alzheimer's disease or family history of alzheimer's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs867611 linked to?
On MyGeneLog this position is linked to Alzheimer's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs867611 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs867611 come from?
GWAS Catalog, Nat Genet 2019, PMID:30617256. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 331422123Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot4Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others23Total33Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
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Alzheimer's disease or family history of Alzheimer's disease (rs867611). MyGeneLog™. https://www.mygenelog.com/variants/rs867611