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Insulin levels in lean individuals

TRIM53CP · rs866817997

What the study found

Who was studied 974 Sub-Saharan African ancestry individuals; replicated in 1,563 African American individuals.

The effect Each copy of the G allele shifted the measure 1.95 higher (95% confidence interval 1.4-2.5); p = 7 × 10−12.

Where it sits Chromosome 11, band 11p11.12 — in an intron of TRIM53CP.

What each result means

G/G Two copies of the version the research linked to Insulin levels in lean individuals. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Insulin levels in lean individuals. That is a smaller link than two copies.
T/T No copy of the version the research linked to Insulin levels in lean individuals. This is the starting point the study compared everyone against.
Source

Questions about rs866817997

What is rs866817997?

rs866817997 is a single position in the genome, in or near the TRIM53CP gene. Published research associates it with insulin levels in lean individuals. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs866817997 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs866817997 come from?

GWAS Catalog, Genome medicine 2021, PMID:34620218. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Insulin levels in lean individuals (rs866817997). MyGeneLog™. https://www.mygenelog.com/variants/rs866817997

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