Major depressive disorder or COVID-19 infection (pleiotropy)
ZSCAN31 · rs853676
2 142219Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others9Total14Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 65,075 European ancestry MDD cases, 112,612 European ancestry COVID-19 infection cases, 2,706,631 European ancestry controls.
The effect
The reported allele is T; the catalogue records no effect size
; p = 3 × 10−10.
Where it sits Chromosome 6, band 6p22.1 — in the 5′ untranslated region of ZSCAN31.
What each result means
C/CNo copy of the version the research linked to Major depressive disorder or COVID-19 infection (pleiotropy). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Major depressive disorder or COVID-19 infection (pleiotropy). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Major depressive disorder or COVID-19 infection (pleiotropy). That is the strongest link of the three results. A link in a study is not a diagnosis.
Frontiers in psychiatry · 2023 · PMID 37426090 · open access
Questions about rs853676
What is rs853676?
rs853676 is a single position in the genome, in or near the ZSCAN31 gene. Published research associates it with major depressive disorder or covid-19 infection (pleiotropy). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs853676 linked to?
On MyGeneLog this position is linked to Major Depressive Disorder. The research behind each link, and its sources, are set out on that condition page.
Does having rs853676 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs853676 come from?
GWAS Catalog, Frontiers in psychiatry 2023, PMID:37426090. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
2 142219Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others9Total14Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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Major depressive disorder or COVID-19 infection (pleiotropy) (rs853676). MyGeneLog™. https://www.mygenelog.com/variants/rs853676