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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 61,745 African ancestry individuals, 6,967 Asian ancestry individuals, 297,166 European ancestry individuals, 26,644 Hispanic or Latin American individuals.
The effect
Each copy of the T allele shifted the measure 0.0291 higher (95% confidence interval 0.025-0.033); p = 2 × 10−52.
Where it sits Chromosome 8, band 8p21.2 — in the 3′ untranslated region of SLC25A37.
What each result means
C/CNo copy of the version the research linked to Prostate-specific antigen levels. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Prostate-specific antigen levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Prostate-specific antigen levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2025 · PMID 39930085 · open access
Questions about rs8534
What is rs8534?
rs8534 is a single position in the genome, in or near the SLC25A37 gene. Published research associates it with prostate-specific antigen levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs8534 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs8534 come from?
GWAS Catalog, Nature genetics 2025, PMID:39930085. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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