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Who was studied 35,474 European ancestry UL cases, 133,384 European ancestry BC cases, 381,294 European ancestry controls.
The effect
The reported allele is A; the catalogue records no effect size
; p = 3 × 10−23.
Where it sits Chromosome 6, band 6q25.1 — in an intron of ESR1.
What each result means
A/ATwo copies of the version the research linked to Uterine leiomyoma or breast cancer (pleiotropy). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Uterine leiomyoma or breast cancer (pleiotropy). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Uterine leiomyoma or breast cancer (pleiotropy). This is the starting point the study compared everyone against.
American journal of human genetics · 2022 · PMID 35803233
Questions about rs851984
What is rs851984?
rs851984 is a single position in the genome, in or near the ESR1 gene. Published research associates it with uterine leiomyoma or breast cancer (pleiotropy). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs851984 linked to?
On MyGeneLog this position is linked to Breast Cancer. The research behind each link, and its sources, are set out on that condition page.
Does having rs851984 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs851984 come from?
GWAS Catalog, American journal of human genetics 2022, PMID:35803233. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 12219Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others9Total12Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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Uterine leiomyoma or breast cancer (pleiotropy) (rs851984). MyGeneLog™. https://www.mygenelog.com/variants/rs851984