Uterine leiomyoma or ER negative breast cancer (pleiotropy)
ESR1 · rs851981
0 00Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others0Total0Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 35,474 European ancestry UL cases, 21,468 European ancestry ER-ve BC cases, 373,479 European ancestry controls.
The effect
The reported allele is A; the catalogue records no effect size
; p = 4 × 10−10.
Where it sits Chromosome 6, band 6q25.1 — in an intron of ESR1.
What each result means
A/ATwo copies of the version the research linked to Uterine leiomyoma or ER negative breast cancer (pleiotropy). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/TOne copy of the version the research linked to Uterine leiomyoma or ER negative breast cancer (pleiotropy). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Uterine leiomyoma or ER negative breast cancer (pleiotropy). This is the starting point the study compared everyone against.
American journal of human genetics · 2022 · PMID 35803233
Questions about rs851981
What is rs851981?
rs851981 is a single position in the genome, in or near the ESR1 gene. Published research associates it with uterine leiomyoma or er negative breast cancer (pleiotropy). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs851981 linked to?
On MyGeneLog this position is linked to Breast Cancer. The research behind each link, and its sources, are set out on that condition page.
Does having rs851981 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs851981 come from?
GWAS Catalog, American journal of human genetics 2022, PMID:35803233. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 00Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others0Total0Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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Uterine leiomyoma or ER negative breast cancer (pleiotropy) (rs851981). MyGeneLog™. https://www.mygenelog.com/variants/rs851981