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Waist-hip index

JAZF1-AS1 · rs849327

What the study found

Who was studied 219,872 British ancestry women.

The effect Each copy of the A allele shifted the measure 0.0215 higher (95% confidence interval 0.016-0.027); p = 5 × 10−13.

Where it sits Chromosome 7, band 7p15.1 — in an intron of JAZF1-AS1.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Waist-hip index compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Waist-hip index.
G/G Published research associates this genotype with typical/baseline likelihood of Waist-hip index — no copies of the reported risk allele.
Source

Questions about rs849327

What is rs849327?

rs849327 is a single position in the genome, in or near the JAZF1-AS1 gene. Published research associates it with waist-hip index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs849327 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs849327 come from?

GWAS Catalog, Scientific reports 2021, PMID:34021172. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Waist-hip index (rs849327). MyGeneLog™. https://www.mygenelog.com/variants/rs849327

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