1 505236223225Reads by AI crawlersClaude5ChatGPT2Google · Gemini0Perplexity3Meta AI6Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others25Total50Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 12,171 European ancestry cases, 56,862 European ancestry controls, 6,952 East Asian ancestry cases, 11,865 East Asian ancestry controls, 5,561 South Asian ancestry cases, 14,458 South Asian ancestry controls, 1,804 Mexican ancestry cases, 779 Mexican ancestry controls; replicated in 21,491 European ancestry cases, 55,647 European ancestry controls.
The effect
Each copy of the G allele carried 1.12 times the odds of Type 2 diabetes (95% confidence interval 1.08-1.17); p = 2 × 10−9.
How common The G allele had a frequency of about 52% in the people studied.
Where it sits Chromosome 7, band 7p15.1 — in an intron of JAZF1.
What each result means
A/ANo copy of the version the research linked to Type 2 diabetes. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Type 2 diabetes. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Type 2 diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs849135
What is rs849135?
rs849135 is a single position in the genome, in or near the JAZF1 gene. Published research associates it with type 2 diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs849135 linked to?
On MyGeneLog this position is linked to Type 2 Diabetes. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs849135?
Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (2 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs849135 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs849135 come from?
GWAS Catalog, Nat Genet 2014, PMID:24509480. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 505236223225Reads by AI crawlersClaude5ChatGPT2Google · Gemini0Perplexity3Meta AI6Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others25Total50Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Type 2 diabetes (rs849135). MyGeneLog™. https://www.mygenelog.com/variants/rs849135