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Hemoglobin levels

SPEN · rs848209

What the study found

Who was studied 684,122 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.015 higher; p = 3 × 10−11.

Where it sits Chromosome 1, band 1p36.13 — a missense change in SPEN.

What each result means

C/C No copy of the version the research linked to Hemoglobin levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Hemoglobin levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Hemoglobin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs848209

What is rs848209?

rs848209 is a single position in the genome, in or near the SPEN gene. Published research associates it with hemoglobin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs848209 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs848209 come from?

GWAS Catalog, Communications biology 2020, PMID:32327693. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Hemoglobin levels (rs848209). MyGeneLog™. https://www.mygenelog.com/variants/rs848209

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