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Digit length ratio

HOXD12 · rs847158

What the study found

Who was studied 12,586 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.242 higher (95% confidence interval 0.17-0.31); p = 1 × 10−10.

How common The A allele had a frequency of about 60% in the people studied.

Where it sits Chromosome 2, band 2q31.1 — between genes, 1.4 kb from HOXD13.

What each result means

A/A Two copies of the version the research linked to Digit length ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Digit length ratio. That is a smaller link than two copies.
G/G No copy of the version the research linked to Digit length ratio. This is the starting point the study compared everyone against.
Source

Questions about rs847158

What is rs847158?

rs847158 is a single position in the genome, in or near the HOXD12 gene. Published research associates it with digit length ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs847158 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs847158 come from?

GWAS Catalog, Hum Mol Genet 2018, PMID:29659830. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Digit length ratio (rs847158). MyGeneLog™. https://www.mygenelog.com/variants/rs847158

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