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Vitamin D-binding protein levels

GC · rs842998

What the study found

Who was studied 2,602 African American individuals.

The effect Each copy of the C allele shifted the measure 0.39 higher (95% confidence interval 0.33-0.45); p = 4 × 10−31.

How common The C allele had a frequency of about 26% in the people studied.

Where it sits Chromosome 4, band 4q13.3 — in an intron of GC.

What each result means

C/C Two copies of the version the research linked to Vitamin D-binding protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Vitamin D-binding protein levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Vitamin D-binding protein levels. This is the starting point the study compared everyone against.
Source

Questions about rs842998

What is rs842998?

rs842998 is a single position in the genome, in or near the GC gene. Published research associates it with vitamin d-binding protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs842998 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs842998 come from?

GWAS Catalog, The American journal of clinical nutrition 2023, PMID:36811574. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Vitamin D-binding protein levels (rs842998). MyGeneLog™. https://www.mygenelog.com/variants/rs842998

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