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Mean platelet volume during second trimester of pregnancy

PDIA5 · rs836848

What the study found

Who was studied 71,605 Chinese ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.053 lower (95% confidence interval 0.038-0.068); p = 2 × 10−11.

How common The G allele had a frequency of about 48% in the people studied.

Where it sits Chromosome 3, band 3q21.1 — in an intron of PDIA5.

What each result means

G/G Two copies of the version the research linked to Mean platelet volume during second trimester of pregnancy. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Mean platelet volume during second trimester of pregnancy. That is a smaller link than two copies.
T/T No copy of the version the research linked to Mean platelet volume during second trimester of pregnancy. This is the starting point the study compared everyone against.
Source

Questions about rs836848

What is rs836848?

rs836848 is a single position in the genome, in or near the PDIA5 gene. Published research associates it with mean platelet volume during second trimester of pregnancy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs836848 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs836848 come from?

GWAS Catalog, Blood 2024, PMID:38064665. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Mean platelet volume during second trimester of pregnancy (rs836848). MyGeneLog™. https://www.mygenelog.com/variants/rs836848

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