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Standard

Height

DAGLB · rs836510

Strength of the evidence

1 / 4

Its strongest genetic-study result is p = 10−8, with 1 associations in the GWAS Catalog.

How this is scored

4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.

What the study found

Who was studied 360,388 European ancestry individuals, 165,056 East Asian ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0084 higher (95% confidence interval 0.0055-0.0113); p = 1 × 10−8.

Where it sits Chromosome 7, band 7p22.1 — in an intron of DAGLB.

How common each version is

CT
Korean KRGDB
C 41.8% · T 58.2%
Korean Korea4K
C 41.6% · T 58.4%
Korean Korea1K
C 41.5% · T 58.5%
Japanese ToMMo
C 39.9% · T 60.1%
Vietnamese
C 49.5% · T 50.5%
World gnomAD
C 64.7% · T 35.3%
World 1000 Genomes
C 55.0% · T 45.0%
World TOPMed
C 62.4% · T 37.6%

The share of all copies of this position that are each version. Source: the population studies published in dbSNP (US NCBI); each row names its study.

What each result means

C/C No copy of the version the research linked to Height. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Height. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Height. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Quoting this page

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Height (rs836510). MyGeneLog™. https://www.mygenelog.com/variants/rs836510

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