GPD1 · rs836179
Where this position leads
Condition: Blood Pressure
What the study found
Who was studied 349,328 British ancestry individuals; replicated in 144,022 European ancestry,African ancestry,Asian ancestry individuals.
The effect Each copy of the A allele shifted the measure 0.03 lower (95% confidence interval 0.026-0.034); p = 4 × 10−30.
Where it sits Chromosome 12, band 12q13.12 — in an intron of GPD1.
What ClinVar records
Classification
Benign; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 2 submitters), last evaluated 2018-09-17.
ClinVar record 1272648 NM_005276.4(GPD1):c.954-124A>G
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
rs836179 is a single position in the genome, in or near the GPD1 gene. Published research associates it with diastolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Nature medicine 2024, PMID:38459180. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Diastolic blood pressure (rs836179). MyGeneLog™. https://www.mygenelog.com/variants/rs836179