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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 32,590 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 8.21 lower; p = 1 × 10−9.
How common The C allele had a frequency of about 74% in the people studied.
Where it sits Chromosome 1, band 1p32.1 — in an intron of FGGY.
What each result means
A/ANo copy of the version the research linked to Ascending aorta maximum area. This is the starting point the study compared everyone against.
A/COne copy of the version the research linked to Ascending aorta maximum area. That is a smaller link than two copies.
C/CTwo copies of the version the research linked to Ascending aorta maximum area. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2022 · PMID 35922433 · open access
Questions about rs835431
What is rs835431?
rs835431 is a single position in the genome, in or near the FGGY gene. Published research associates it with ascending aorta maximum area. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs835431 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs835431 come from?
GWAS Catalog, Nature communications 2022, PMID:35922433. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Ascending aorta maximum area (rs835431). MyGeneLog™. https://www.mygenelog.com/variants/rs835431