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Vertex-wise sulcal depth

CADPS · rs833653

What the study found

Who was studied 33,748 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 8.62 z score higher; p = 7 × 10−18.

How common The T allele had a frequency of about 38% in the people studied.

Where it sits Chromosome 3, band 3p14.2 — in an intron of CADPS.

What each result means

C/C No copy of the version the research linked to Vertex-wise sulcal depth. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Vertex-wise sulcal depth. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Vertex-wise sulcal depth. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs833653

What is rs833653?

rs833653 is a single position in the genome, in or near the CADPS gene. Published research associates it with vertex-wise sulcal depth. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs833653 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs833653 come from?

GWAS Catalog, Science advances 2021, PMID:34910505. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Vertex-wise sulcal depth (rs833653). MyGeneLog™. https://www.mygenelog.com/variants/rs833653

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