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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 400 French ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.225 ug/mL lower (95% confidence interval 0.2-0.25); p = 1 × 10−34.
Where it sits Chromosome 3, band 3p21.31 — in the 3′ untranslated region of EXOSC7.
What each result means
A/ANo copy of the version the research linked to Tetranectin plasma levels. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Tetranectin plasma levels. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Tetranectin plasma levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Genome medicine · 2022 · PMID 35264221 · open access
Questions about rs8318
What is rs8318?
rs8318 is a single position in the genome, in or near the EXOSC7 gene. Published research associates it with tetranectin plasma levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs8318 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs8318 come from?
GWAS Catalog, Genome medicine 2022, PMID:35264221. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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