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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 35,657 White British ancestry individuals.
The effect
The reported allele is A; the catalogue records no effect size
; p = 1 × 10−17.
How common The A allele had a frequency of about 43% in the people studied.
Where it sits Chromosome 1, band 1q32.1 — between genes, 4.9 kb from NUCKS1.
What each result means
A/ATwo copies of the version the research linked to Cortical thickness. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Cortical thickness. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Cortical thickness. This is the starting point the study compared everyone against.
rs823121 is a single position in the genome, in or near the near NUCKS1 gene. Published research associates it with cortical thickness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs823121 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs823121 come from?
GWAS Catalog, NeuroImage 2021, PMID:34560273. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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