Sensitive

Urinary metabolite levels in chronic kidney disease

GLDC · rs820503

What the study found

Who was studied 1,221 cases; replicated in 406 cases.

The effect Each copy of the A allele shifted the measure 0.292 lower (95% confidence interval 0.23-0.35); p = 3 × 10−22.

How common The A allele had a frequency of about 14% in the people studied.

Where it sits Chromosome 9, band 9p24.1 — in an intron of LINC02851.

What each result means

A/A Two copies of the version the research linked to Urinary metabolite levels in chronic kidney disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Urinary metabolite levels in chronic kidney disease. That is a smaller link than two copies.
C/C No copy of the version the research linked to Urinary metabolite levels in chronic kidney disease. This is the starting point the study compared everyone against.
Source

Questions about rs820503

What is rs820503?

rs820503 is a single position in the genome, in or near the GLDC gene. Published research associates it with urinary metabolite levels in chronic kidney disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs820503 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs820503 come from?

GWAS Catalog, Nature genetics 2020, PMID:31959995. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Urinary metabolite levels in chronic kidney disease (rs820503). MyGeneLog™. https://www.mygenelog.com/variants/rs820503

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