Toll/interleukin-1 receptor domain-containing adapter protein levels
TIRAP · rs8177399
0 20142328Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot4Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others8Total20Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 10,708 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.734 lower (95% confidence interval 0.65-0.82); p = 5 × 10−60.
How common The T allele had a frequency of about 2% in the people studied.
Where it sits Chromosome 11, band 11q24.2 — a missense change in TIRAP.
What each result means
C/CNo copy of the version the research linked to Toll/interleukin-1 receptor domain-containing adapter protein levels. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Toll/interleukin-1 receptor domain-containing adapter protein levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Toll/interleukin-1 receptor domain-containing adapter protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs8177399 is a single position in the genome, in or near the TIRAP gene. Published research associates it with toll/interleukin-1 receptor domain-containing adapter protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs8177399 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs8177399 come from?
GWAS Catalog, Science (New York, N.Y.) 2021, PMID:34648354. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 20142328Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot4Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others8Total20Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
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Toll/interleukin-1 receptor domain-containing adapter protein levels (rs8177399). MyGeneLog™. https://www.mygenelog.com/variants/rs8177399