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Endometriosis or asthma (pleiotropy)

RUNX1 · rs8133814

Where this position leads

Condition: Asthma

rs8133814 Condition: Asthma Asthma Condition rs8133814 rs8133814 RUNX1

What the study found

Who was studied 17,054 European, Japanese ancestry endometriosis cases, 26,332 European, Japanese ancestry asthma cases, 567,363 European, Japanese ancestry controls.

The effect Each copy of the C allele shifted the measure 0.05 higher; p = 3 × 10−9.

Where it sits Chromosome 21, band 21q22.12 — inside RUNX1.

What each result means

C/C Two copies of the version the research linked to Endometriosis or asthma (pleiotropy). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Endometriosis or asthma (pleiotropy). That is a smaller link than two copies.
G/G No copy of the version the research linked to Endometriosis or asthma (pleiotropy). This is the starting point the study compared everyone against.
Source

Questions about rs8133814

What is rs8133814?

rs8133814 is a single position in the genome, in or near the RUNX1 gene. Published research associates it with endometriosis or asthma (pleiotropy). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs8133814 linked to?

On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.

Does having rs8133814 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs8133814 come from?

GWAS Catalog, Human reproduction (Oxford, England) 2022, PMID:35472084. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Endometriosis or asthma (pleiotropy) (rs8133814). MyGeneLog™. https://www.mygenelog.com/variants/rs8133814

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