0 61212Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others2Total6Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 62,976 European ancestry individuals, 6,238 Hispanic or Latin American individuals, 5,034 East Asian ancestry individuals, 2,437 African American individuals, 310 South Asian ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.85 lower; p = 5 × 10−17.
How common The C allele had a frequency of about 49% in the people studied.
Where it sits Chromosome 21, band 21q21.3 — in an intron of BACH1.
What each result means
C/CTwo copies of the version the research linked to QT interval. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to QT interval. That is a smaller link than two copies.
T/TNo copy of the version the research linked to QT interval. This is the starting point the study compared everyone against.
rs8133749 is a single position in the genome, in or near the BACH1 gene. Published research associates it with qt interval. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs8133749 linked to?
On MyGeneLog this position is linked to QT Interval and Drug-Induced Long QT. The research behind each link, and its sources, are set out on that condition page.
Does having rs8133749 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs8133749 come from?
GWAS Catalog, Genetics 2022, PMID:36271874. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 61212Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others2Total6Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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