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Age at first birth

IER2 · rs8110682

What the study found

Who was studied 542,901 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0695 lower (95% confidence interval 0.048-0.091); p = 3 × 10−10.

How common The T allele had a frequency of about 63% in the people studied.

Where it sits Chromosome 19, band 19p13.13 — between genes, 15.7 kb from RPL12P42.

What each result means

C/C No copy of the version the research linked to Age at first birth. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Age at first birth. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Age at first birth. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs8110682

What is rs8110682?

rs8110682 is a single position in the genome, in or near the IER2 gene. Published research associates it with age at first birth. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs8110682 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs8110682 come from?

GWAS Catalog, Nature human behaviour 2021, PMID:34211149. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Age at first birth (rs8110682). MyGeneLog™. https://www.mygenelog.com/variants/rs8110682

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