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Who was studied 4,383 Mexican ancestry individuals; replicated in 7,876 Latin American/Hispanic individuals, European ancestry individuals (Global Lipids Genetics Consortium et al, 2013).
The effect
Each copy of the G allele shifted the measure 0.252 higher (95% confidence interval 0.2-0.31); p = 3 × 10−18.
How common The G allele had a frequency of about 96% in the people studied.
Where it sits Chromosome 19, band 19p13.11 — in an intron of MAU2.
What each result means
A/ANo copy of the version the research linked to Triglycerides. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Triglycerides. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Triglycerides. That is the strongest link of the three results. A link in a study is not a diagnosis.
Scientific reports · 2016 · PMID 26780889 · open access
Questions about rs8102280
What is rs8102280?
rs8102280 is a single position in the genome, in or near the MAU2 gene. Published research associates it with triglycerides. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs8102280 linked to?
On MyGeneLog this position is linked to High Triglycerides. The research behind each link, and its sources, are set out on that condition page.
Does having rs8102280 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs8102280 come from?
GWAS Catalog, Scientific reports 2016, PMID:26780889. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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