PP14A protein level (protein group normalized intensity)
SPINT2 · rs8101725
0 9135Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon1Apple3China (ByteDance, Huawei, Baidu…)0Others5Total9Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 1,156 European, Hispanic or African ancestry individuals; replicated in 325 Arab, Indian or Filipino ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.236 lower (95% confidence interval 0.15-0.32); p = 4 × 10−8.
How common The T allele had a frequency of about 38% in the people studied.
Where it sits Chromosome 19, band 19q13.2 — in an intron of SPINT2.
What each result means
C/CNo copy of the version the research linked to PP14A protein level (protein group normalized intensity). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to PP14A protein level (protein group normalized intensity). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to PP14A protein level (protein group normalized intensity). That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2025 · PMID 41310232 · open access
Questions about rs8101725
What is rs8101725?
rs8101725 is a single position in the genome, in or near the SPINT2 gene. Published research associates it with pp14a protein level (protein group normalized intensity). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs8101725 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs8101725 come from?
GWAS Catalog, Nature genetics 2025, PMID:41310232. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 9135Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon1Apple3China (ByteDance, Huawei, Baidu…)0Others5Total9Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
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PP14A protein level (protein group normalized intensity) (rs8101725). MyGeneLog™. https://www.mygenelog.com/variants/rs8101725