IL29 · rs8099917
Where this position leads
Condition: Chronic Hepatitis C
Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.
What the study found
Who was studied 1,015 European ancestry chronic HCV carriers, 347 European ancestry spontaneously cleared HCV individuals.
The effect Each copy of the G allele carried 2.31 times the odds of Chronic hepatitis C infection (95% confidence interval 1.74-3.06); p = 6 × 10−9.
How common The G allele had a frequency of about 24% in the people studied.
Where it sits Chromosome 19, band 19q13.2 — between genes, 1.5 kb from MSRB1P1.
What ClinVar records
Classification
drug response for interferons, peginterferon alfa-2a, peginterferon alfa-2b, and ribavirin response - Efficacy, peginterferon alfa-2a, peginterferon alfa-2b, ribavirin, and telaprevir response - Efficacy; reviewed by expert panel (3 of 4 stars, 2 submitters), last evaluated 2021-03-29.
ClinVar record 226027 NC_000019.10:g.39252525T>G
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What people read about alongside this
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
rs8099917 is a single position in the genome, in or near the IL29 gene. Published research associates it with chronic hepatitis c infection. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Chronic Hepatitis C. The research behind each link, and its sources, are set out on that condition page.
Subjects that appear in the title or abstract of the same papers as this rsID include infection and immunity (100 papers), liver (72 papers), blood sugar and insulin (13 papers), cholesterol and blood fats (6 papers), vitamins and nutrient levels (4 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Gastroenterology 2010, PMID:20060832. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Chronic hepatitis C infection (rs8099917). MyGeneLog™. https://www.mygenelog.com/variants/rs8099917