Sialic acid-binding Ig-like lectin 15 level in Chronic kidney disease with hypertension and no diabetes (10847_1)
SIGLEC15 · rs8084290
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 466 African American individuals.
The effect
Each copy of the G allele shifted the measure 0.6 lower (95% confidence interval 0.46-0.74); p = 6 × 10−17.
How common The G allele had a frequency of about 23% in the people studied.
Where it sits Chromosome 18, band 18q12.3 — in an intron of SIGLEC15.
What each result means
A/ANo copy of the version the research linked to Sialic acid-binding Ig-like lectin 15 level in Chronic kidney disease with hypertension and no diabetes (10847_1). This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Sialic acid-binding Ig-like lectin 15 level in Chronic kidney disease with hypertension and no diabetes (10847_1). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Sialic acid-binding Ig-like lectin 15 level in Chronic kidney disease with hypertension and no diabetes (10847_1). That is the strongest link of the three results. A link in a study is not a diagnosis.
rs8084290 is a single position in the genome, in or near the SIGLEC15 gene. Published research associates it with sialic acid-binding ig-like lectin 15 level in chronic kidney disease with hypertension and no diabetes (10847_1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs8084290 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs8084290 come from?
GWAS Catalog, Kidney international 2022, PMID:35870639. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 422Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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Sialic acid-binding Ig-like lectin 15 level in Chronic kidney disease with hypertension and no diabetes (10847_1) (rs8084290). MyGeneLog™. https://www.mygenelog.com/variants/rs8084290