Standard

Hypertension (PheCode 401)

GIP · rs8078510

Where this position leads

Condition: Blood Pressure

rs8078510 Condition: Blood Pressure Blood Pressure Condition rs8078510 rs8078510 GIP

What the study found

Who was studied 94,292 African American or Afro-Caribbean cases, 22,643 African American or Afro-Caribbean controls, 35,766 Hispanic or Latin American cases, 20,913 Hispanic or Latin American controls, 3,903 East Asian ancestry cases, 2,607 East Asian ancestry controls, 322,448 European ancestry cases, 105,690 European ancestry controls.

The effect Each copy of the G allele shifted the measure 0.0542 higher (95% confidence interval 0.041-0.067); p = 1 × 10−17.

How common The G allele had a frequency of about 73% in the people studied.

Where it sits Chromosome 17, band 17q21.32 — in an intron of GIP.

What each result means

A/A No copy of the version the research linked to Hypertension (PheCode 401). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Hypertension (PheCode 401). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Hypertension (PheCode 401). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs8078510

What is rs8078510?

rs8078510 is a single position in the genome, in or near the GIP gene. Published research associates it with hypertension (phecode 401). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs8078510 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs8078510 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs8078510 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hypertension (PheCode 401) (rs8078510). MyGeneLog™. https://www.mygenelog.com/variants/rs8078510

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