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Omega-3 fatty acids to Omega-6 fatty acids ratio

near PEMT · rs8074074

What the study found

Who was studied 239,268 European ancestry individuals.

The effect The reported allele is C; the catalogue records no effect size ; p = 5 × 10−13.

Where it sits Chromosome 17, band 17p11.2 — between genes, 1.1 kb from PEMT.

What each result means

C/C Two copies of the version the research linked to Omega-3 fatty acids to Omega-6 fatty acids ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Omega-3 fatty acids to Omega-6 fatty acids ratio. That is a smaller link than two copies.
T/T No copy of the version the research linked to Omega-3 fatty acids to Omega-6 fatty acids ratio. This is the starting point the study compared everyone against.
Source

Questions about rs8074074

What is rs8074074?

rs8074074 is a single position in the genome, in or near the near PEMT gene. Published research associates it with omega-3 fatty acids to omega-6 fatty acids ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs8074074 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs8074074 come from?

GWAS Catalog, HGG advances 2025, PMID:40545721. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Omega-3 fatty acids to Omega-6 fatty acids ratio (rs8074074). MyGeneLog™. https://www.mygenelog.com/variants/rs8074074

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