Standard

Asthma

IKZF3 · rs8071789

Where this position leads

Condition: Asthma

rs8071789 Condition: Asthma Asthma Condition rs8071789 rs8071789 IKZF3

What the study found

Who was studied 12,093 African American or Afro-Caribbean cases, 105,134 African American or Afro-Caribbean controls, 5,688 Hispanic or Latin American cases, 52,071 Hispanic or Latin American controls, 609 East Asian ancestry cases, 6,004 East Asian ancestry controls, 36,823 European ancestry cases, 398,278 European ancestry controls.

The effect Each copy of the C allele shifted the measure 0.0558 higher (95% confidence interval 0.041-0.07); p = 1 × 10−15.

How common The C allele had a frequency of about 48% in the people studied.

Where it sits Chromosome 17, band 17q21.1 — in an intron of IKZF3.

What each result means

C/C Two copies of the version the research linked to Asthma. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Asthma. That is a smaller link than two copies.
T/T No copy of the version the research linked to Asthma. This is the starting point the study compared everyone against.
Source

Questions about rs8071789

What is rs8071789?

rs8071789 is a single position in the genome, in or near the IKZF3 gene. Published research associates it with asthma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs8071789 linked to?

On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.

Does having rs8071789 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs8071789 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Asthma (rs8071789). MyGeneLog™. https://www.mygenelog.com/variants/rs8071789

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