Standard

White matter hyperintensities

DCAKD · rs8071429

What the study found

Who was studied 39,011 European ancestry individuals, 2,099 African ancestry individuals, 795 Hispanic individuals, 3,299 Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 8.11 Zscore higher; p = 3 × 10−16.

Where it sits Chromosome 17, band 17q21.31 — in the 5′ untranslated region of NMT1.

What each result means

A/A Two copies of the version the research linked to White matter hyperintensities. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to White matter hyperintensities. That is a smaller link than two copies.
T/T No copy of the version the research linked to White matter hyperintensities. This is the starting point the study compared everyone against.
Source

Questions about rs8071429

What is rs8071429?

rs8071429 is a single position in the genome, in or near the DCAKD gene. Published research associates it with white matter hyperintensities. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs8071429 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs8071429 come from?

GWAS Catalog, Nature communications 2020, PMID:32358547. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

White matter hyperintensities (rs8071429). MyGeneLog™. https://www.mygenelog.com/variants/rs8071429

← See all variants