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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 344,104 European ancestry individuals, 133,471 East Asian ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0225 higher (95% confidence interval 0.016-0.029); p = 2 × 10−11.
Where it sits Chromosome 17, band 17p11.2 — in an intron of MPRIP.
What each result means
C/CNo copy of the version the research linked to Gamma glutamyl transpeptidase. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Gamma glutamyl transpeptidase. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Gamma glutamyl transpeptidase. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs8064991 is a single position in the genome, in or near the MPRIP gene. Published research associates it with gamma glutamyl transpeptidase. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs8064991 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs8064991 come from?
GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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