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Chronotype

near GNPATP · rs8063159

What the study found

Who was studied 449,734 European ancestry individuals; replicated in 248,098 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0145 higher (95% confidence interval 0.011-0.018); p = 7 × 10−17.

How common The A allele had a frequency of about 39% in the people studied.

Where it sits Chromosome 16, band 16q21 — between genes, 60.6 kb from GNPATP.

What each result means

A/A Two copies of the version the research linked to Chronotype. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Chronotype. That is a smaller link than two copies.
C/C No copy of the version the research linked to Chronotype. This is the starting point the study compared everyone against.
Source

Questions about rs8063159

What is rs8063159?

rs8063159 is a single position in the genome, in or near the near GNPATP gene. Published research associates it with chronotype. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs8063159 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs8063159 come from?

GWAS Catalog, Nature communications 2019, PMID:30696823. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Chronotype (rs8063159). MyGeneLog™. https://www.mygenelog.com/variants/rs8063159

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