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Kynurenine levels

SLC7A5 · rs8050771

What the study found

Who was studied 2,466 Black/admixed ancestry individuals; replicated in up to 1,653 European, Hispanic, Asian or Black individuals.

The effect Each copy of the A allele shifted the measure 0.216 higher (95% confidence interval 0.16-0.27); p = 5 × 10−14.

Where it sits Chromosome 16, band 16q24.2 — in an intron of SLC7A5.

What each result means

A/A Two copies of the version the research linked to Kynurenine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Kynurenine levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Kynurenine levels. This is the starting point the study compared everyone against.
Source

Questions about rs8050771

What is rs8050771?

rs8050771 is a single position in the genome, in or near the SLC7A5 gene. Published research associates it with kynurenine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs8050771 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs8050771 come from?

GWAS Catalog, Nature communications 2022, PMID:35995766. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Kynurenine levels (rs8050771). MyGeneLog™. https://www.mygenelog.com/variants/rs8050771

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