0 18223110Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others10Total18Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 71,771 European ancestry cases, 7,482 African ancestry cases, 189 South Asian ancestry cases, 507 East Asian ancestry cases, 1,720 Hispanic cases, 1,426,717 controls.
The effect
Each copy of the A allele shifted the measure 0.137 higher (95% confidence interval 0.088-0.185); p = 4 × 10−8.
How common The A allele had a frequency of about 2% in the people studied.
Where it sits Chromosome 16, band 16q24.1 — in an intron of C16orf74.
What each result means
A/ATwo copies of the version the research linked to Venous thromboembolism. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Venous thromboembolism. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Venous thromboembolism. This is the starting point the study compared everyone against.
rs8049403 is a single position in the genome, in or near the C16orf74 gene. Published research associates it with venous thromboembolism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs8049403 linked to?
On MyGeneLog this position is linked to Venous Thromboembolism. The research behind each link, and its sources, are set out on that condition page.
Does having rs8049403 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs8049403 come from?
GWAS Catalog, Circulation 2022, PMID:36154123. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 18223110Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot2Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others10Total18Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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