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Sleep (number of episodes)

GPR139 · rs8045740

What the study found

Who was studied 84,810 European ancestry individuals; replicated in 4,401 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.052 higher (95% confidence interval 0.038-0.066); p = 6 × 10−14.

How common The G allele had a frequency of about 87% in the people studied.

Where it sits Chromosome 16, band 16p12.3 — between genes, 12.2 kb from SNRPEP3.

What each result means

G/G Two copies of the version the research linked to Sleep (number of episodes). That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Sleep (number of episodes). That is a smaller link than two copies.
T/T No copy of the version the research linked to Sleep (number of episodes). This is the starting point the study compared everyone against.
Source

Questions about rs8045740

What is rs8045740?

rs8045740 is a single position in the genome, in or near the GPR139 gene. Published research associates it with sleep (number of episodes). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs8045740 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs8045740 come from?

GWAS Catalog, Nature communications 2019, PMID:30952852. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Sleep (number of episodes) (rs8045740). MyGeneLog™. https://www.mygenelog.com/variants/rs8045740

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