C/CPublished research associates this genotype with typical/baseline likelihood of Post bronchodilator FEV1/FVC ratio — no copies of the reported risk allele.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Post bronchodilator FEV1/FVC ratio.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Post bronchodilator FEV1/FVC ratio compared to the general population.
rs8039449 is a single position in the genome, in or near the CHRNB4 gene. Published research associates it with post bronchodilator fev1/fvc ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs8039449 linked to?
On MyGeneLog this position is linked to Pulmonary Function (Lung Capacity). The research behind each link, and its sources, are set out on that condition page.
Does having rs8039449 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs8039449 come from?
GWAS Catalog, BMC Genet 2015, PMID:26634245. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.