Sensitive

Attention deficit hyperactivity disorder

SEMA6D · rs8039398

Where this position leads

Condition: ADHD (Attention Deficit Hyperactivity Disorder)

rs8039398 Condition: ADHD (Attention Deficit Hyperactivity Disorder) ADHD (Attention Deficit Hyperactivi… Condition rs8039398 rs8039398 SEMA6D

What the study found

Who was studied 14,154 European ancestry male cases, 17,948 European ancestry male controls.

The effect Each copy of the T allele shifted the measure 0.094 lower (95% confidence interval 0.061-0.127); p = 3 × 10−8.

Where it sits Chromosome 15, band 15q21.1 — in an intron of SEMA6D.

What each result means

C/C No copy of the version the research linked to Attention deficit hyperactivity disorder. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Attention deficit hyperactivity disorder. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Attention deficit hyperactivity disorder. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs8039398

What is rs8039398?

rs8039398 is a single position in the genome, in or near the SEMA6D gene. Published research associates it with attention deficit hyperactivity disorder. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs8039398 linked to?

On MyGeneLog this position is linked to ADHD (Attention Deficit Hyperactivity Disorder). The research behind each link, and its sources, are set out on that condition page.

Does having rs8039398 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs8039398 come from?

GWAS Catalog, Biol Psychiatry 2017, PMID:29325848. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Attention deficit hyperactivity disorder (rs8039398). MyGeneLog™. https://www.mygenelog.com/variants/rs8039398

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